treatments

Polynucleotide (Salmon DNA, PDRN)

Polynucleotides have emerged as a revolutionary ingredient in the world of aesthetic treatments. They are naturally occurring molecules that play a crucial role in cellular functions and tissue repair.


In dermatology, they are utilized for their regenerative properties, promoting skin health and rejuvenation.
overview

Rediscover Your Radiant Self

Polynucleotide injections are also known as Sodium DNA, Salmon DNA, and PDRN.

Polynucleotide injection offers a revolutionary approach to skin rejuvenation. It is a non-surgical cosmetic procedure that involves injecting a concentrated solution of polynucleotides into the skin, or undergoing a series of three mesoneedling sessions to infuse the booster into the skin.

At Respa Palm Beach, we utilize Toskani Med’s Lumicen Ampoule with mesoneedling—a superficial microneedling technique—to infuse the  rich in polynucleotide serum into the skin. This process involves:

  • Microneedling: Tiny needles create micro-injuries in the skin, enhancing absorption of the active ingredients.
  • Infusion: As the skin heals, the polynucleotides penetrate deeply, maximizing their rejuvenating effects.
  • No Downtime: Patients can return to their daily activities immediately after treatment, with minimal redness or swelling.

Derived from salmon roe, these natural compounds stimulate collagen and elastin production, enhancing skin firmness and reducing wrinkles.

treatment Highlights

Skin Hydration

Polynucleotides help retain moisture, resulting in plumper, more youthful skin.

Enhanced Elasticity

By promoting collagen synthesis, they improve skin elasticity and firmness.

Reduced Inflammation

They have anti-inflammatory properties, making them beneficial for sensitive or irritated skin.

Quick Results

Many patients notice improvements even after a single session, with optimal results developing over time.

Minimally Invasive

The application process is gentle, typically involving minimal downtime.

Safe Treatment

It is generally considered safe when performed by trained and qualified professionals.

How it Works

Polynucleotides work by stimulating the skin's natural repair and regeneration processes. When applied to the skin, these compounds promote collagen and elastin production. Collagen and elastin are essential proteins that provide structure and elasticity to the skin. By stimulating their production, polynucleotides help improve skin firmness, reduce wrinkles, and enhance overall skin texture.

The polynucleotide solution is injected into the targeted areas using a fine needle. The injections are usually performed in a series of small "dots" or "bumps" or through mesoneedling.

Once infused into the skin, they enhance hydration, support skin cell renewal, reduce inflammation, and promote a radiant glow.

Why Consider Polynucleotide Treatment?

Polynucleotide treatments are primarily used to address various skin concerns, including wrinkles and fine lines, loss of volume in the face, dryness, uneven skin tone, and hair loss. Common treatment areas include:

  • Face: Forehead, cheeks, crow's feet, nasolabial folds, and lips   
  • Neck: To address sagging skin and wrinkles   
  • Hands: To improve skin texture and reduce age spots

Why Polynucleotides Are Better Than Other Treatments

Compared to traditional fillers or Botox, polynucleotides offer a more holistic approach to skin rejuvenation. They not only address surface-level concerns but also promote deeper skin regeneration.
Unlike fillers, which can create volume, polynucleotides work by enhancing the skin’s natural structure, leading to more natural-looking results. They also carry a lower risk of side effects and complications.
results

Treatments that Work

PRP facial rejuvenation has shown promising results in improving skin texture and tone. Existing studies indicate that PRP can effectively lead to significant facial enhancements by stimulating collagen production and increasing hyaluronic acid levels.

Many patients report increased skin firmness and a more youthful appearance following a series of treatments. Other facial improvements include reducing wrinkles and fine lines, eliminating pigmented spots, and reducing pore size.

Polynucleotide (Salmon DNA, PDRN) For Skin Rejuvenation

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reduction in incontinence pad use

Polynucleotides (PDRN) are naturally occurring molecules that play a crucial role in cellular functions and tissue repair. In dermatology, they are utilized for their regenerative properties, promoting skin health and rejuvenation.

Polynucleotide injections are made from naturally derived DNA fragments, often sourced from salmon (Sodium DNA) or other fish. 

These DNA fragments are composed of nucleotides that promote cell regeneration, reduce inflammation, and boost skin hydration. They are safe, biocompatible, and help stimulate tissue repair.

The treatment involves undergoing a series of three mesoneedling sessions to infuse the booster into the skin. Each session typically takes around 30 minutes to an hour, depending on the treatment area. Numbing cream may be applied to ensure comfort. 

Our PDRN skin booster stimulates skin rejuvenation or tissue repair, promoting natural healing.

The number of treatments varies depending on your goals and the area being treated. Generally, 3 to 5 sessions spaced 2 to 4 weeks apart are recommended to achieve optimal results. Your ReSpa healthcare provider will assess your needs and recommend a tailored treatment plan.

Polynucleotide injections have minimal downtime. You might experience mild swelling, redness, or bruising at the injection site, which usually subsides within 24 to 48 hours. 

Most patients can resume normal activities immediately after the procedure, though it’s advised to avoid strenuous exercise for a day or two.

Our PDRN skin booster is ideal for individuals seeking to improve skin hydration, reduce fine lines, or promote healing in damaged tissues. 

It’s also beneficial for those with mild to moderate signs of aging or skin conditions.

Results may start to appear after the first session, but most patients notice significant improvement after 2 to 3 sessions. Full results are typically seen a few weeks after completing the entire treatment series, as the polynucleotides work to stimulate long-term tissue repair and rejuvenation.

To maximize your results, follow your doctor’s aftercare instructions, which may include staying hydrated, applying gentle skincare products, and avoiding sun exposure or harsh treatments for a few days after the procedure. Consistency with the recommended treatment plan will also enhance outcomes.

Wear comfortable, loose-fitting clothing to your appointment, especially if you are getting treated in an area like the legs or arms. This will ensure easy access to the treatment site and help you feel more relaxed during the procedure.

Polynucleotide treatments can often be combined with other skincare treatments, such as microneedling, Emface, and PRP facial rejuvenation, to enhance results. This can include:

However, it's important to discuss your goals with your healthcare provider at our spa in Palm Beach Gardens to ensure a customized treatment plan.

Why Choose ReSpa Palm Beach?

We have seen exceptional results with our polynucleotide treatments, even after just one session. Our use of Toskani Med Lumicen Ampoules ensures that you receive a high-quality product specifically designed for skin rejuvenation.
Our skilled professionals prioritize your comfort and satisfaction, guiding you through the treatment process for optimal outcomes.

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DISCLAIMER
The material contained on this site is for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE, and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare providers with any questions or concerns you may have regarding your health.